Mathew Blurton-Jones Selected Research

Neuroinflammatory Diseases

1/2023	Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features.
12/2017	Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.
4/2016	Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.
3/2016	The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.

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Mathew Blurton-Jones Research Topics

Disease

24	Alzheimer Disease (Alzheimer's Disease) 12/2023 - 07/2004
10	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 11/2008
6	Inflammation (Inflammations) 01/2023 - 04/2009
6	Cognitive Dysfunction 01/2022 - 07/2004
5	Dementia (Dementias) 05/2022 - 11/2015
5	Synucleinopathies 01/2022 - 11/2015
4	Neuroinflammatory Diseases 01/2023 - 03/2016
4	Parkinson Disease (Parkinson's Disease) 05/2022 - 01/2012
3	Huntington Disease (Huntington's Disease) 01/2018 - 01/2017
3	Tauopathies 11/2017 - 01/2016
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 08/2012
2	Frontotemporal Dementia (Semantic Dementia) 01/2021 - 08/2013
2	Amyloid Plaque 12/2019 - 02/2005
2	Disease Progression 01/2017 - 07/2015
2	Memory Disorders (Memory Loss) 01/2016 - 08/2009
1	Fibrosis (Cirrhosis) 03/2024
1	Neoplasm Metastasis (Metastasis) 12/2023
1	Chromosome 3-Linked Frontotemporal Dementia 10/2023
1	Hypersensitivity (Allergy) 01/2022
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021
1	Edema (Dropsy) 01/2020
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2020
1	Bites and Stings (Sting) 12/2017
1	Neuroblastoma 11/2017
1	Proteostasis Deficiencies 01/2016
1	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia 08/2013
1	Muscular Diseases (Myopathy) 08/2013
1	Osteitis Deformans (Paget's Disease of Bone) 08/2013
1	Nervous System Diseases (Neurological Disorders) 07/2011

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 10/2023 - 08/2009
10	Amyloid beta-PeptidesIBA 06/2023 - 07/2004
7	Amyloid (Amyloid Fibrils)IBA 01/2022 - 08/2009
6	SynucleinsIBA 05/2022 - 01/2012
5	VaccinesIBA 06/2023 - 11/2017
3	RNA (Ribonucleic Acid)IBA 03/2024 - 01/2021
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2016 - 08/2009
3	CaspasesIBA 02/2005 - 07/2004
2	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 11/2017
2	DNA VaccinesIBA 01/2020 - 11/2017
2	Peptides (Polypeptides)IBA 01/2020 - 01/2019
2	EpitopesIBA 01/2020 - 11/2017
2	AntibodiesIBA 11/2017 - 11/2017
1	Apolipoproteins E (ApoE)IBA 12/2023
1	ApolipoproteinsIBA 12/2023
1	Glutamine (L-Glutamine)FDA Link 10/2023
1	Pyrrolidonecarboxylic Acid (Pyroglutamic Acid)IBA 06/2023
1	ClusterinIBA 01/2023
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 01/2022
1	Adenosine Diphosphate (ADP)IBA 01/2022
1	ProteomeIBA 01/2022
1	C9orf72 ProteinIBA 01/2021
1	DipeptidesIBA 01/2021
1	Ligases (Synthetase)IBA 12/2017
1	Interferon Type IIBA 12/2017
1	Mitochondrial DNA (mtDNA)IBA 12/2017
1	Therapeutic UsesIBA 10/2017
1	Glutamic Acid (Glutamate)FDA Link 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2017
1	Monoclonal AntibodiesIBA 01/2017
1	CytokinesIBA 03/2016
1	Cocaine (Cocaine HCl)IBA 01/2016
1	trkB ReceptorIBA 01/2016
1	UbiquitinIBA 08/2013
1	Valosin Containing ProteinIBA 08/2013
1	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2012
1	Indicators and Reagents (Reagents)IBA 07/2011
1	Nerve Growth Factors (Neurotrophins)IBA 05/2011
1	alpha-SynucleinIBA 05/2010
1	PresenilinsIBA 08/2009
1	Tumor Necrosis Factor InhibitorsIBA 04/2009
1	Cell Cycle ProteinsIBA 01/2009
1	Protein AggregatesIBA 11/2008

Therapy/Procedure

7	Transplantation 01/2018 - 08/2009
4	Therapeutics 01/2023 - 07/2004
3	Immunotherapy 12/2023 - 01/2017
1	Transcutaneous Electric Nerve Stimulation (TENS) 06/2017
1	Investigational Therapies (Experimental Therapy) 07/2015